A new study suggests that Depo-Provera can reduce the risk of breast cancer by up to 25 percent in women who use it for contraception.
The new study, published in theBritish Medical Journal, showed that women who took the drug for three months had a 15 percent increased risk of developing a second or third breast cancer.
The risk of developing breast cancer increases with long-term use.
In the analysis, researchers found that the risk was increased by 15 percent for women who had used Depo-Provera every three months for five years or longer, while the rate was still 15 percent higher for those who took the drug every three months for seven years or longer.
The study was published in the, in March, and the drug has already been linked to a 10 percent increased risk of breast cancer in women who used the drug for three months or more.
A second study that included over 3,000 women and showed that the drug reduces the risk of developing breast cancer by up to 25 percent, the drug’s manufacturer, Pfizer, said in a statement.
The women who took the drug had a five-fold increase in risk of developing breast cancer, which is the most common type of cancer diagnosed in women. It is also the third most common type of cancer in women in the United States, and is the most common cause of preventable death.
“This is an important result that is important because it’s the first data we have on the effect of long-term use of this drug on breast cancer risk,” Dr. Susan E. White, an epidemiologist at the University of California, San Diego School of Medicine and professor of endocrinology at the University of California, San Diego, told ABC News.
The results of the new analysis were presented today at the annual Scientific Sessions in the U. S. If they are true, they suggest that the risks of developing breast cancer in women who use Depo-Provera may be far higher than they otherwise would be. That would increase the risk of developing a third or fourth breast cancer, which is the most common type of cancer.
Depo-Provera is a contraceptive method that has been shown to reduce the risk of breast cancer by about 25 percent. That’s about the same as the risk of breast cancer for other hormonal birth control methods such as the pill, implant, intrauterine device and condom.
The new study was funded by Pfizer, which sells the contraceptive drug. Pfizer said the study found no significant differences in the risk of developing breast cancer between women who used Depo-Provera and those who didn’t. The women who took the drug had a five-fold increase in risk, according to the study.
The study is the latest effort by Pfizer to investigate the connection between long-term use of contraceptives and breast cancer. The study was led by Dr. Elizabeth Doherty, a epidemiologist at the University of Oxford who is a past president of the American College of Obstetricians and Gynecologists.
Dr. Doherty said she was concerned about the study because it was the first to examine the effect of hormonal birth control on breast cancer risk.
“The study was designed to look at the effect of hormonal birth control on breast cancer risk,” she said in a statement. “This was an important study because it would provide an important insight into the link between hormonal birth control and breast cancer risk.”
But Dr. Robert H. Bixen, a professor of medicine at Harvard Medical School and a member of the Women’s Health Initiative and the American College of Obstetricians and Gynecologists, said that the new study is the first to link hormonal birth control to breast cancer risk.
He added: “The association of hormonal birth control with breast cancer risk was observed in women who took the drug for three months or more. The study is the first to link hormonal birth control with a reduction in the risk of developing breast cancer.”
The results should spur more research into the connection between long-term use of contraceptives and the development of breast cancer.
The study was published online inThe New England Journal of Medicine, in May.
Elizabeth Doherty, who is also the study’s lead author, said: “This study is the latest effort by Pfizer to investigate the connection between long-term use of contraceptives and breast cancer.
Product name:Depo-Provera Injection
Company name:
DIN:0229905
Status:Marketed
Status date:2025-08-16
| Active ingredient(s) | Strength |
|---|---|
| Progesterone | 100mcg/mL |
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The Product Monograph is a scientific document that describes the properties, claims, indications and conditions of use of the product and contains any other information that may be required for optimal, safe and effective use. The Product Monograph includes three sections:
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Depo-SubQ Provera 104 needs to be given by subcutaneous (hypodermic) injection once every 12 weeks. This is not an intramuscular injection and must be given by someone trained and knowledgeable on how to give a subcutaneous injection.
The main active ingredient in Depo-SubQ Provera 104 is Medroxyprogesterone acetate 104 mg.
The risks are low, but some women experience side effects when using Depo-SubQ Provera 104. Minor ones include (spotting) or some gain weight. Positive side effects are also a possibility, too — lighter bleeds are fairly common.
The chances of serious side effects from birth control pills are extremely unlikely, but some cases have been documented, such as unexplained vaginal bleeding, severe pelvic pain, severe abdominal pain, and bone pain. Depo-SubQ 104 has been associated with lower bone mineral density (BMD). However, pregnancy results in a greater potential loss of BMD. This method is not recommended for younger patients who have not yet reached their peak bone mass or patients with osteoporosis. Alternatives to Depo-SubQ Provera would be the pill, patch, ring.
If you experience swelling/itching of your face/throat/tongue, trouble breathing, or severe dizziness, this may indicate an allergic reaction, please call 911 or get to the emergency room to receive appropriate emergency medical treatment.
Do NOT take this medication if:
• you are allergic to medroxyprogesterone acetate or any of the other ingredients of this medication• you have a history ofbson renal cell cancer• you have had seizures/convulsions with medications that lower blood pressure or exacerbate it
You have severe liver or kidney problemsThis medication should not be used in any way except by you
Other pregnancy results can affect pregnancy. This medication should not be used in women who are pregnant or who shouldn't be pregnant.This medication is contraindicated in children and women with a known history of seizures/convulsions.
This medication should not be used in children or women with a history of them being pregnant.This medication should not be used in any way other than last-minute. It is especially recommended to avoid taking this medication during phase 3 of pregnancy, as this results in anovulation and may lead to preterm delivery. Depo-SubQ 104 must be given by someone trained and knowledgeable on the technique and knowledge required to give a subcutaneous injection.
Depo-SubQ 104 dose may change at any time.This medication is contraindicated in patients with a history of blood clots, blood disorders, uncontrolled high blood pressure, liver or kidney problems, and/or glaucoma. It is generally not recommended to use this medication in women who are pregnant during this phase.
References10-田-84958-7This is not a complete list of contraindications and should be read before starting treatment with this medication. If you have contraindications, discuss them with your doctor or pharmacist. Tell your doctor or pharmacist about any prescription or over-the-counter (OTC) medication you are taking.
This medication is not recommended for use in pregnant or breastfeeding women unless clearly needed. Because of the possible for the infant, this medication should be used only when clearly needed during pregnancy. Important: Follow all directions on your prescription label and package. Store Depo-SubQ 104 at room temperature away from excess moisture and heat.
Q: What is PROVERA 10MG TABLET used for?
A: PROVERA 10MG TABLET is used in to maintain a balance on menstrual cycle and controls abnormal tissue growth in uterus.
Q: How does PROVERA 10MG TABLET regulate menstrual cycle?
A: PROVERA 10MG TABLET works by stopping the production of gonadotropin hormone, which is responsible for maturation of cells in the ovary and the process of releasing mature egg from the ovary (ovulation) to avoid pregnancy. This kind of action provides relief from unpleasant period symptoms.
Q: For how long should you take PROVERA 10MG TABLET?
A: Your doctor might advise you on how long you should continue to take PROVERA 10MG TABLET. You will need to consult your doctor from time to time to review your management and assess your symptoms. Do not stop taking PROVERA 10MG TABLET on your own.
Q: Can PROVERA 10MG TABLET be used during pregnancy?
A: PROVERA 10MG TABLET is not recommended for use in pregnant women as it can affect the developing baby. If you think you are pregnant or planning to have baby or have a history of repeated miscarriage, inform your doctor before taking PROVERA 10MG TABLET. Use other methods of contraceptives while taking this medicine.
Q:IsPROVERA 10MG TABLET safe to use in patients with heart problems?
A: PROVERA 10MG TABLET is not recommended for use if patient had a stroke or heart attack in the past years. It should be taken with caution in patients with heart problems and high blood pressure. Consult your doctor before taking PROVERA 10MG TABLET.
How do you take PROVERA 10MG TABLET: How do I know if I have ovulation problems?In the case of women with ovarian cancer, taking PROVERA 10MG TABLET may may lead to ovarian cancer with possible synergising effect. The complete course of treatment for treatment was decided based on symptoms and laboratory parameters.
How long do I need to take PROVERA 10MG TABLET?For women who are takingPROVERA 10MG TABLET for longer than a week, it is advised to take different contraceptive methods from tablet to tablet. The most common method prescribed by your doctor is oral (medicinal vaginal ring, pills and past/current medical history), pill, and patch. Your doctor will decide how much treatment you will need after several months of follow-up. If you have any questions regarding other methods of contraception, consult your doctor.
Depo-Provera, a hormone contraceptive injection, is given every three months to prevent pregnancy.
This medicine is the most widely used hormone contraceptive, used to prevent pregnancy for over 30 years.
Depo-Provera is a synthetic progestin that contains a progestin hormone. This medicine may be given to women who cannot take other hormones, like menopause symptoms, as a shot that can cause irregular periods.
The progestin is injected subcutaneously into a woman’s vagina, and it works to prevent pregnancy by stopping ovulation.
After this injection, the woman is capable of having children. Depo-Provera is given every three months to prevent pregnancy, but it is not available as a regular contraceptive pill.
Women should never use Depo-Provera.
If you are planning to become pregnant, talk to your doctor about alternative contraception or a different contraceptive method.
There are a number of other alternatives to Depo-Provera, including birth control pills, injectable contraception and birth control injection.
If you are considering using Depo-Provera, you should talk to your doctor or pharmacist about alternative birth control methods or birth control pills.